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Xing X, Wang H, Niu T, Jiang Y, Shi X, Liu K. RUNX1 can mediate the glucose and O-GlcNAc-driven proliferation and migration of human retinal microvascular endothelial cells. BMJ open diabetes research & care 2021 9(1) 34348917
Abstract:
This study aims to determine whether high glucose condition and dynamic O-linked N-acetylglucosamine (O-GlcNAc) modification can promote the proliferation and migration of human retinal microvascular endothelial cells (HRMECs) and whether Runt-related transcription factor 1 (RUNX1) could mediate the glucose and O-GlcNAc-driven proliferation and migration of HRMECs.
O-GlcNAc proteins:
RUNX1
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