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Li R, Ong Q, Wong CC, Chu ESH, Sung JJY, Yang X, Yu J. O-GlcNAcylation inhibits hepatic stellate cell activation. Journal of gastroenterology and hepatology 2021 36(12) 34547820
Protein O-GlcNAcylation is a critical post-translational modification regulating gene expression and fundamental cell functions. O-GlcNAc transferase (OGT) emerged as a key regulator of liver pathophysiology and disease. In this study, we aimed to evaluate the role of OGT in hepatic stellate cells (HSCs) and its consequent role in liver fibrosis.
O-GlcNAc proteins:
Species: Mus musculus
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